After PrePex placement and removal, weekly visits assessed wound healing. Men returned on Day Safety was defined as occurrence of moderate and serious clinical AEs. Efficacy was defined as ability to reach the endpoint of complete circumcision. All AEs were device displacements resulting in surgical MC and, subsequently, complete healing. Demographic and behavioural risk factors associated with Trichomonas vaginalis among South African HIV-positive men with genital ulcer disease: a cross-sectional study.
Demographic and risky sexual behaviours may increase the risk for Trichomonas vaginalis TV infection and, thus, enhance HIV transmission to uninfected partners. We assessed the demographic and behavioural risk factors associated with TV among South African HIV-positive men with genital ulcer disease. We conducted a cross-sectional study with data from a randomised controlled trial conducted by the Centers for Disease Control and Prevention and the London School of Hygiene and Tropical Medicine. The data were obtained from three primary healthcare clinics in South Africa.
The outcome TV was measured using real-time multiplex PCR assays and a Rotor-gene platform from the first and past urine samples of all participants. An estimated The odds of TV infection were significantly associated with high blister counts OR 4. Multivariate analyses revealed that increased days with ulcers OR 0.
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Minority stress theory represents the most plausible conceptual framework for explaining health disparities for gay and bisexual men GBM. We explored the role of HIV-related stress within a minority stress model of mental health and condomless anal sex. Longitudinal data were collected on a diverse convenience sample of highly sexually active, HIV-positive GBM in NYC regarding sexual minority internalized homonegativity and gay-related rejection sensitivity and HIV-related stressors internalized HIV stigma and HIV-related rejection sensitivity , emotion dysregulation, mental health symptoms of depression, anxiety, sexual compulsivity, and hypersexuality , and sexual behavior condomless anal sex with all male partners and with serodiscordant male partners.
Across both sexual minority and HIV-related stressors, internalized stigma was significantly associated with mental health and sexual behavior outcomes while rejection sensitivity was not. We identified two targets of behavioral interventions that may lead to improvements in mental health and reductions in sexual transmission risk behaviors-maladaptive cognitions underlying negative self-schemas and difficulties with emotion regulation.
Techniques for cognitive restructuring and emotion regulation may be particularly useful in the development of interventions that are sensitive to the needs of this population while also highlighting the important role that structural interventions can have in preventing these disparities for future generations. Multiple strategies to identify HIV-positive black men who have sex with men and transgender women in New York City: a cross-sectional analysis of recruitment results.
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Black men who have sex with men and transgender women are at high risk for HIV infection, but are more likely to be unaware of their infection or not in care for diagnosed HIV compared to other races. Respondent driven sampling has been advanced as a method to reach stigmatized and hidden populations for HIV testing.
We compared strategies to recruit black, substance-using men who have sex with men and transgender women to identify newly diagnosed HIV infection, or those previously diagnosed but not in care. Respondent-driven sampling, community-based recruitment and online advertising were used to recruit participants.
Incentivized peer referral was integrated into all recruitment strategies. Participants completed interviewer-administered questionnaires and HIV testing. Demographic and HIV risk-related characteristics and recruitment strategy were summarized and stratified by HIV status. Associations were tested using Pearson's chi-squared, Fisher's exact, and Wilcoxon rank sum tests.
Integrating multiple recruitment strategies yielded a large sample of black men who have sex with men and transgender women at substantial risk for HIV. Respondent-driven sampling was less effective than other strategies at identifying men who have sex with men and transgender women with HIV. Increased mortality among HIV-positive men on antiretroviral therapy: survival differences between sexes explained by late initiation in Uganda. We also specifically examined the role of antenatal services in favoring women's access to HIV care.
Methods: From an observational cohort study, we assessed survival and used logistic regression and differences in means to compare men and women who did not access care through antenatal services. Differences were assessed on measures of disease progression WHO stage and CD4 count and demographic age, marital status, and education, behavioral sexual activity, disclosure to partner, and testing, and clinical variables hepatitis B and C, syphilis, malaria, and anemia. A mediational analysis that considered gender as the initial variable, time to death as the outcome, initial CD4 count as the mediator, and age as a covariate was performed using an accelerated failure time model with a Weibull distribution.
Results: Between and , a total of patients initiated ART, and after exclusions In a prospective, observational study, participants were administered surveys at baseline and months 6 and 12, with measures including sexual behavior, internalized HIV stigma, and an egocentric social network assessment that included several measures of perceived HIV stigma among alters.
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In longitudinal multivariable models comparing the relative predictive value of internalized stigma versus various measures of alter stigma, significant predictors of having had condomless intercourse included greater internalized HIV stigma in all models , the perception that a popular well-connected alter or alter most like the participant agrees with an HIV stigma belief, and the interaction of network density with having any alter that agrees with a stigma belief.
The interaction indicated that the protective effect of greater density connectedness between alters in terms of reduced risk behavior dissipated in the presence of perceived alter stigma. These findings call for interventions that help people living with HIV to cope with their diagnosis and reduce stigma, and inform the targets of social network-based and peer-driven HIV prevention interventions. Change in subjective social status following HIV diagnosis and associated effects on mental and physical health among HIV-positive gay men in Australia.
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This study investigates the impact of HIV diagnosis on subjective social status and if changes are linked to health outcomes. Two measures of subjective social status, socio-economic and standing in the community were examined in Australian HIV-positive gay men in Participants recalled ratings at diagnosis were compared with current ratings. Self-reported mental psychological distress, self-esteem, positive mental health and satisfaction with life and physical health self-rated health, CD4 count, viral load.
Increases in either measure of subjective social status were linked to higher self-esteem, positive mental health, satisfaction with life and better self-rated health. Decreases in subjective social status, however, were strongly linked to poorer outcomes on all mental health measures. Decreases in standing in the community were also associated with poorer physical self-rated health.
Most participants reported their subjective social status were the same or better since diagnosis. Changes in subjective social status following diagnosis were strongly linked to mental health outcomes. Those who reported a decrease in subjective social status were particularly vulnerable to mental health problems. Can additive measures add to an intersectional understanding? Experiences of gay and ethnic discrimination among HIV-positive Latino gay men.
The current study investigated a methodological question of whether traditional, additive, quantitative data can be used to address intersectional issues, and illustrated such an approach with a sample of HIV-positive , Latino gay men in the United States. Hierarchical logistic set regression investigated the role of sets of variables reflecting demographic characteristics, gender nonconformity, and gay and ethnic discrimination in relation to depression and gay collective identity.
Results showed the discrimination set was related to depression and to gay collective identity, as was gender nonconformity. Follow-up logistic regression showed that both types of discrimination were associated with greater depression, but gender nonconformity was not. Gay discrimination and gender nonconformity were positively associated with gay collective identity, whereas ethnic discrimination was negatively associated. Results are discussed in terms of the use of traditional quantitative data as a potential means of understanding intersectional issues, as well as of contributing to knowledge about individuals facing multiple structural inequalities.
Preventing transmission from virally unsuppressed men who have condomless anal sex CAS with serodiscordant partners is a public health imperative. New HIV infections in GBMSM are attributed in part to online access to sex partners; therefore, low-cost eHealth interventions are a unique opportunity to reach men where they meet partners.
To describe the protocol of a randomized controlled trial evaluating whether video-based messaging delivered online may lead to reductions in serodiscordant CAS and increased HIV disclosure. Sex Positive! Participants in the intervention arm receive 10 video vignettes grounded in social learning and social cognitive theories that are designed to elicit critical thinking around issues of HIV transmission and disclosure.
Participants in the attention control arm receive 10 video vignettes that focus on healthy living. All videos are optimized for mobile viewing. Compared to the control arm, we hypothesize that men who watch the intervention videos will report at month follow-up significantly fewer serodiscordant CAS partners, increased HIV disclosure, and improved social cognition eg, condom use self-efficacy, perceived responsibility. Participant recruitment began in June and ended in December This protocol describes the underlying theoretical framework and.
On days participants drank they were significantly more likely to be medication non-adherent and to have unprotected sex. In the first day after their alcohol consuming day, the pattern of nonadherence persisted. Binge and regular drinking days were associated with nonadherence but only binge drinking co-occurred with unprotected sex. Asking about specific "drinking days" improved recall for drinking days and number of drinks consumed. There was high concordance and low discordance between A-TLFB drinking and nonadherence but these results were reversed for unprotected sex.
Moving beyond simple drinking-adherence correlational analysis, the A-TLFB offers improved recall probes and provides researchers and interventionists with the opportunity to identify types of risky days and tailor behavioral modification to reduce alcohol consumption, nonadherence and risky sex on those days. What drives the number of high-risk human papillomavirus types in the anal canal in HIV-positive men who have sex with men? We estimated the effect of sexual behavior, age, and immunodeficiency on the number of high-risk human papillomavirus HR-HPV types in the anal canal among human immunodeficiency virus-positive men who have sex with men MSM.
We conducted a randomized controlled trial of a combined motivational interview MI and cognitive behavioral therapy CBT intervention tailored specifically to the unique context of HIV-positive GBM, and tested whether IMB profiles moderated treatment effects. Increase in sexually transmitted infections in a cohort of outpatient HIV-positive men who have sex with men in the Parisian region. We performed a monocentric, retrospective, and prospective study. One hundred and eighty patients were seen between and between We observed an increased incidence of STIs between the two periods 14 and These STIs includes: syphilis, hepatitis C, urethritis, and proctitis due to Chlamydia trachomatis and Neisseria gonorrhea.
Prevalences were expressed as a proportion and compared using chi-square.
Active syphilis Chlamydia and gonorrhea were infrequent in both groups. Regardless of HIV infection status, age and number of lifetime male sexual partners were associated with HBV infection and lifetime injection drug use with HCV infection. This argues for the implementation of routine screening, vaccine-based prevention, and education programs in this high-risk population. Peer counselling versus standard-of-care on reducing high-risk behaviours among newly diagnosed HIV-positive men who have sex with men in Beijing, China: a randomized intervention study.
Reducing high-risk behaviours i. We designed an intervention to explore peer- counselling in reducing high-risk behaviours among newly diagnosed HIV-positive Chinese men who have sex with men MSM. SOC participants received counselling on high-risk behaviour reduction by clinic staff. Intervention participants received both SOC and peer counselling.
Both intent-to-treat and per-protocol full-dosage approaches were used for the analyses. Peer counselling had a greater impact in reducing condomless anal sex with men , illicit drug use and condomless vaginal sex with women over time.
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Future studies with exclusive peer-counselling arm are necessary to test its efficacy and effectiveness among Chinese MSM. HIV-positive men who have sex with men : biography, diversity in lifestyles, common experience of living with HIV. The conceptualisation of male who have sex with male MSM to account for male homosexual behaviour has been developed to facilitate the endorsement of prevention message since the advent of HIV infection. Population studies performed to understand and monitor sexual and preventive behaviour usually recruit respondents through gay-friendly channels such as media, sexual venues or festivals, leading to recruitment bias.
Few studies question possible differences according to varying sexual biography and current behaviour within the MSM population. Among the respondents, men reported a lifetime male sexual partner. Information regarding sexual biography lifetime and current numbers of male and female sexual partners, lifetime number of male and female stable couples was computed using cluster analysis and identified five profiles: exclusive gay The profiles matched self-identification better among the most exclusive homosexuals than among men with current bisexuality.
These five subgroups differed regarding demographic and social characteristics except migration status , their period of diagnosis, age and CD4 count at diagnosis. Sexual activity, steady partnership, number of male and female partners, use of sexual venues and illegal substance use were different across subgroups. Specimens testing positive in cobas but not in LA were more likely to be positive for other markers of HPV-related disease compared to those testing negative in both assays, suggesting that at least some of these were true positives for HPV.
A combination of anal cytology and HPV genotyping provided the highest accuracy for detecting anal precancer. All Rights Reserved. Box-Cox transformation and normal distribution tests were used to describe the general distribution characteristics of the original and transformed data of PVL, then the stable distribution function was fitted with test of goodness of fit.
Results: The original PVL data fitted a skewed distribution with the variation coefficient of Conclusions: The original PVL data had some censored data below the detection limit, and the data over the detection limit had abnormal distribution with large degree of variation. When proportion of the censored data was large, it was inappropriate to use half-value of detection limit to replace the censored ones.